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KPV 10mg

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cGMP Manufacturing

All Instrips products are manufactured in cGMP-compliant facilities with strict adherence to quality standards. Full chain-of-custody documentation ensures traceability, reliability, and reproducibility for research purposes.

Research Applications

Designed for precision research, these peptides support a wide range of experimental protocols. Ideal for laboratory studies requiring consistent, reproducible compound delivery.

Safety & Compliance

All products are intended for research use only. Follow standard lab safety guidelines, including proper protective equipment and waste disposal protocols.

KPV (Lys-Pro-Val) is a synthetic tripeptide derived from the C-terminal sequence of ฮฑ-melanocyte-stimulating hormone (ฮฑ-MSH).

It is known for its potent anti-inflammatory properties, acting independently of melanocortin receptors by modulating NF-ฮบB signaling and reducing pro-inflammatory cytokine production. In research models, KPV is studied for its ability to support gut barrier integrity, promote tissue healing, reduce intestinal inflammation, and provide benefits in dermatological and systemic inflammatory conditions.

Key Research Areas:

  • Anti-inflammatory and immunomodulatory effects
  • Gastrointestinal health and IBD models
  • Skin repair, wound healing, and dermatological applications
  • Cytokine regulation and oxidative stress
  • Tissue protection and recovery studies

Compound Information๐Ÿงช

Technical specifications

Molecular Profile

What Is KPV?

Type Synthetic tripeptide
Sequence Lys-Pro-Val (KPV)
Amino acids 3
Molecular formula Cโ‚โ‚†Hโ‚ƒโ‚€Nโ‚„Oโ‚„
Molecular weight 342.43 g/mol
CAS Number 67727-97-3
Origin ฮฑ-MSH residues 11-13

PubChem Database

Parent Compound

Relationship to ฮฑ-MSH

Parent peptide ฮฑ-Melanocyte-Stimulating Hormone
ฮฑ-MSH length 13 amino acids
KPV position C-terminal (11-13)
Activity retained Anti-inflammatory effects
MCR binding NOT required for activity

Br J Pharmacol Review

Storage Requirements

Stability Information

Freeze for storage
Refrigerate after reconstitutionย  Protect from light
Lyophilized (powder)
โ„๏ธ-20ยฐC long-term
Reconstituted
โ„๏ธ2-8ยฐCโ€ขuse within 7 days
Light protection
Store away from light

๐Ÿ“šSources & References

Gastroenterology

Gastroenterology

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

2008โ€ขDOI:ย 10.1053/j.gastro.2007.10.026โ€ขPMID:ย 18061177

Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al.

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British Journal of Pharmacology

British Journal of Pharmacology

ฮฑ-MSH Related Peptides: A New Class of Anti-Inflammatory and Immunomodulating Drugs

2000โ€ขDOI:ย 10.1111/j.1476-5381.2000.00178.x

Luger TA, Brzoska T, Scholzen TE, et al.

View Source
Molecular Pharmaceutics

Molecular Pharmaceutics

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

2017โ€ขPMID:ย 28548842

Xiao B, Xu Z, Viennois E, et al.

View Source
Annals of the New York Academy of Sciences

Annals of the New York Academy of Sciences

Melanocortin-Derived Tripeptide KPV Has Anti-Inflammatory Potential in Murine Models of Inflammatory Bowel Disease

2008โ€ขPMID:ย 18226903

Kannengiesser K, Maaser C, Heidemann J, et al.

View Source

โš ๏ธImportant Research Notice

Not for human consumption.ย This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

Weight.4 oz
Dimensions.6 × .6 × 1.4 in
Size10mg

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All products offered on our website are accompanied by a Certificate of Analysis (COA) to ensure quality, purity, and consistency for research purposes.

Each batch undergoes rigorous analytical testing performed by qualified laboratories using validated methods such as High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). These tests verify the identity, purity, and composition of the product.

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