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LGF-1LR3 1mg

cGMP Manufacturing

All Instrips products are manufactured in cGMP-compliant facilities with strict adherence to quality standards. Full chain-of-custody documentation ensures traceability, reliability, and reproducibility for research purposes.

Research Applications

Designed for precision research, these peptides support a wide range of experimental protocols. Ideal for laboratory studies requiring consistent, reproducible compound delivery.

Safety & Compliance

All products are intended for research use only. Follow standard lab safety guidelines, including proper protective equipment and waste disposal protocols.

IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a synthetic, modified version of the naturally occurring IGF-1 peptide with an extended half-life and enhanced potency.

It acts as a potent growth factor that promotes cell proliferation, differentiation, and survival. In research settings, IGF-1 LR3 is studied for its ability to stimulate muscle growth (hypertrophy), support tissue repair, enhance nutrient uptake, and promote anabolic processes through activation of the IGF-1 receptor pathway.

Key Research Areas:

  • Muscle growth and hypertrophy models
  • Tissue repair and regeneration
  • Cellular proliferation and anti-aging research
  • Metabolic regulation and nutrient partitioning
  • Recovery from injury and performance studies

Compound Information🧪

Technical specifications

Molecular Profile

What Is IGF-1 LR3?

Type  Synthetic IGF-1 analog
CAS Number 143045-27-6
Molecular Weight 9,117.60 g/mol
Amino Acids 83
Formula C400H625N111O115S9
Sequence MFPAMPLSSL FVNGPRTLCG…

PubChem Database

Structural Modifications

How It Differs from Native IGF-1

N-terminal extension+13 amino acids (MFPAMPLLSLFVN)
Position 3 substitutionGlu → Arg
Total length83 vs 70 amino acids
IGFBP affinity Dramatically reduced
IGF-1R affinity Retained

Mohan & Baylink, 2002

📚Sources & References

Biochemical Journal

Biochemical Journal

Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats

1992•DOI: 10.1042/bj2820091•PMID: 1371669

Tomas FM, Knowles SE, Owens PC et al.

View Source
Journal of Endocrinology

Journal of Endocrinology

Superior potency of infused IGF-I analogues which bind poorly to IGF-binding proteins is maintained when administered by injection

1996•DOI: 10.1677/joe.0.1500077•PMID: 8708565

Tomas FM, Lemmey AB, Read LC, Ballard FJ

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Journal of Endocrinology

Journal of Endocrinology

IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

2002•DOI: 10.1677/joe.0.1750019•PMID: 12379487

Mohan S, Baylink DJ

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American Journal of Pathology

American Journal of Pathology

IGF-1 has plaque-stabilizing effects in atherosclerosis by altering vascular smooth muscle cell phenotype

2011•DOI: 10.1016/j.ajpath.2010.10.007•PMID: 21281823

von der Thüsen JH, Borensztajn KS, Moimas S et al.

View Source
Journal of Endocrinology

Journal of Endocrinology

Long R3 insulin-like growth factor-I (IGF-I) infusion stimulates organ growth but reduces plasma IGF-I, IGF-II and IGF binding protein concentrations in the guinea pig

1995•DOI: 10.1677/joe.0.1460247•PMID: 7561636

Conlon MA, Tomas FM, Owens PC et al.

View Source

⚠️Important Research Notice

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

Weight.4 oz
Dimensions.6 × .6 × 1.4 in
Size1mg

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All products offered on our website are accompanied by a Certificate of Analysis (COA) to ensure quality, purity, and consistency for research purposes.

Each batch undergoes rigorous analytical testing performed by qualified laboratories using validated methods such as High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). These tests verify the identity, purity, and composition of the product.

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