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TB-500 10mg

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Research Applications

Designed for precision research, these peptides support a wide range of experimental protocols. Ideal for laboratory studies requiring consistent, reproducible compound delivery.

Safety & Compliance

All products are intended for research use only. Follow standard lab safety guidelines, including proper protective equipment and waste disposal protocols.

TB-500 (Thymosin Beta-4 fragment) is a synthetic peptide that mimics a naturally occurring protein involved in actin regulation and tissue repair.

It promotes cell migration, differentiation, and wound healing by facilitating actin polymerization and angiogenesis. In research models, TB-500 is studied for its systemic effects on tissue regeneration, flexibility, inflammation reduction, and recovery from muscle, tendon, and ligament injuries.

Key Research Areas:

  • Tissue repair and regeneration (muscles, tendons, ligaments)
  • Wound healing and injury recovery
  • Actin regulation and cell migration
  • Anti-inflammatory effects
  • Cardiovascular and systemic recovery models

Compound Information๐Ÿงช

Technical specifications

Molecular Profile

What Is TB-500?

Type Endogenous peptide/synthetic analog
CAS Number 77591-33-4
Molecular Weight 4,963 Da
Amino Acids 43
Active Region Ac-SDKP (N-terminal)
Key Sequence 17LKKTET22 (actin binding)

Expert Opin Biol Ther (2012)

Storage Requirements

Stability Information

Protect from lightย 
โ„๏ธย Lyophilized (powder)
-20ยฐCโ€ขstable long-term
๐Ÿ’‰Reconstituted
2-8ยฐCโ€ขuse within 14-30 days
ย Avoid
Repeated freeze-thaw cycles

๐Ÿ“šSources & References

Expert Opinion on Biological Therapy

Expert Opinion on Biological Therapy

Thymosin ฮฒ4: a multi-functional regenerative peptide. Basic properties and clinical applications

2012โ€ขDOI:ย 10.1517/14712598.2012.634793โ€ขPMID:ย 22074294

Goldstein AL, Hannappel E, Sosne G, Kleinman HK

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Annals of the New York Academy of Sciences

Annals of the New York Academy of Sciences

A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta4 in healthy volunteers

2010โ€ขDOI:ย 10.1111/j.1749-6632.2010.05474.xโ€ขPMID:ย 20536472

Ruff D, Crockford D, Girardi G, Zhang Y

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Journal of the Neurological Sciences

Journal of the Neurological Sciences

A Dose Response Study of Thymosin ฮฒ4 for the Treatment of Acute Stroke

2014โ€ขDOI:ย 10.1016/j.jns.2014.07.006โ€ขPMID:ย 25060418

Morris DC, Cui Y, Cheung WL, Lu M, Zhang L, Zhang ZG, Chopp M

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Journal of Investigative Dermatology

Journal of Investigative Dermatology

Thymosin beta4 accelerates wound healing

1999โ€ขDOI:ย 10.1046/j.1523-1747.1999.00708.xโ€ขPMID:ย 10469335

Malinda KM, Sidhu GS, Mani H, Banaudha K, Maheshwari RK, Goldstein AL, Kleinman HK

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International Journal of Molecular Sciences (PMC)

International Journal of Molecular Sciences (PMC)

Progress on the Function and Application of Thymosin ฮฒ4

2021โ€ขDOI:ย 10.3390/ijms222413136

Xing Y, et al.

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Nature

Nature

Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair

2004โ€ขDOI:ย 10.1038/nature03000โ€ขPMID:ย 15565145

Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D

View Source
Clinical Ophthalmology

Clinical Ophthalmology

Thymosin beta 4 ophthalmic solution for dry eye: a randomized, placebo-controlled, Phase II clinical trial

2015โ€ขDOI:ย 10.2147/OPTH.S80954โ€ขPMID:ย 26056426

Sosne G, Ousler GW

View Source
Neuroscience

Neuroscience

Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke

2010โ€ขDOI:ย 10.1016/j.neuroscience.2010.05.017โ€ขPMID:ย 20627173

Morris DC, Chopp M, Zhang L, Lu M, Zhang ZG

View Source
Journal of Neurosurgery

Journal of Neurosurgery

Treatment of traumatic brain injury with thymosin beta4 in rats

2010โ€ขDOI:ย 10.3171/2010.4.JNS10118โ€ขPMID:ย 20486893

Xiong Y, Mahmood A, Meng Y, Zhang Y, Zhang ZG, Morris DC, Chopp M

View Source
Nature
Nature

Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization

2007โ€ขDOI:ย 10.1038/nature05383โ€ขPMID:ย 17108969

Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, Chien KR, Riley PR

View Source

ย 

โš ๏ธImportant Research Notice

Not for human consumption.ย This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

Weight.4 oz
Dimensions.6 × .6 × 1.4 in
Size10mg, 20mg

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All products offered on our website are accompanied by a Certificate of Analysis (COA) to ensure quality, purity, and consistency for research purposes.

Each batch undergoes rigorous analytical testing performed by qualified laboratories using validated methods such as High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). These tests verify the identity, purity, and composition of the product.

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