Research Peptides

Melanotan 2

Name: Melanotan 2
Brand: Riptide Peptides
Availability: OutOfStock

≥99% purityLyophilized powderThird-party COA

Melanotan 2 is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.

$29.99

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Certificate of analysis

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⚠ Research use only. This product is intended solely for in-vitro laboratory research by qualified professionals. Not for human or veterinary use.

Research overview

About Melanotan 2

Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH).

It acts as a potent agonist at melanocortin receptors (primarily MC1R and MC4R). In research models, Melanotan 2 is studied for its ability to stimulate melanogenesis (melanin production), resulting in increased skin pigmentation and potential photoprotective effects against UV damage. It is also researched for its influences on appetite suppression, energy balance, and sexual function via central nervous system pathways.

Key Research Areas

Skin pigmentation and UV photoprotection
Appetite regulation and metabolic studies
Sexual arousal and libido models
Melanocortin receptor signaling pathways
Energy homeostasis and weight management

Molecular Profile

Melanotan II Structure

Synthetic cyclic heptapeptide analog of α-MSH

Cyclic Peptideα /MSH Analog

CAS Number: 121062-08-6
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.18 g/mol
Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Structure: Cyclic lactam

Receptor Binding

Melanocortin Receptor Affinity

MC1R: High affinity (pigmentation)
MC3R: Moderate (metabolism)
MC4R: High affinity (sexual function)
MC5R: Moderate (exocrine)

Physical Properties

Formulation Characteristics

Handling and storage requirements

Appearance: White lyophilized powder
Solubility: Soluble in water
Storage: 2-8°C (refrigerated)
Reconstituted stability: 30 days refrigerated

Sources & references5 peer-reviewed publications and databases

British Journal of Dermatology
A randomized controlled trial of melanotan II in the induction of eumelanin synthesis in fair-skinned subjects
Barnetson RS, et al.
2006 · PMID: 16293341
Urology
Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study
Wessells H, et al.
1998 · PMID: 9679884
Life Sciences
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
Dorr RT, et al.
1996 · PMID: 8831529
Peptides
Discovery and development of novel melanogenic drugs. Melanotan-I and -II
Hadley ME, Dorr RT
2006 · PMID: 16289566
International Journal of Impotence Research
An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist
Diamond LE, et al.
2004 · PMID: 15073503

Research summaries and references are drawn from published, peer-reviewed literature and are provided for educational reference only. They are not product claims or medical advice. This product is sold strictly for laboratory research and is not for human or veterinary use.

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