Molecular Profile
What Is DSIP?
Naturally occurring nonapeptide
Nonapeptide Endogenous
- Type
- Synthetic nonapeptide
- CAS Number
- 62568-57-4 C35H48N10O15
- Molecular Weight
- 848.8 g/mol
- Amino Acids
- 9 residues
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Research Peptides
DSIP
≥99% purityLyophilized powderThird-party COA
DSIP is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.
$29.99
1
- ✓ Same-day dispatch
- ✓ Discreet packaging
- ✓ Third-party tested batch
- ✓ COA available
Certificate of analysis
The report for the current batch is available on request. Request it here.
DSIP is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.
⚠ Research use only. This product is intended solely for in-vitro laboratory research by qualified professionals. Not for human or veterinary use.
Research overview
About DSIP
DSIP (Delta Sleep-Inducing Peptide) is a synthetic nonapeptide originally studied for its role in regulating sleep and neuroendocrine function.
In research models, DSIP has been investigated for its potential to promote deep (delta) sleep, modulate stress responses (via ACTH and cortisol regulation), exhibit antioxidant properties, and influence pain perception and withdrawal symptoms. It is one of the earlier peptides studied in the field of sleep neurochemistry.
Key Research Areas
- Sleep regulation and delta wave enhancement
- Stress response and HPA axis modulation
- Neuroprotection and antioxidant effects
- Pain management and analgesic models
- Substance withdrawal and neuroendocrine studies
Storage Requirements
Stability Information
Handle with care to maintain potency
Light sensitiveTemperature sensitive
- Lyophilized (powder)
- -20°C · Protect from light
- Reconstituted
- 2-8°C · Use within 24 hours
- Stability
- 15 minutes (plasma half-life)
Sources & references9 peer-reviewed publications and databases
European Journal of Anaesthesiology
Pollard BJ, Pomfrett CJD
2001
International Journal of Clinical Pharmacology, Therapy, and Toxicology
Acute and delayed effects of DSIP on human sleep behavior
Schneider-Helmert D, et al.
1981 · PMID: 6895513
Neuropsychobiology
Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients
Bes F, Hofman W, Schuur J, Van Boxtel C
1992 · DOI: 10.1159/000118919 · PMID: 1299794
European Neurology
DSIP in the treatment of withdrawal syndromes from alcohol and opiates
Dick P, Costa C, Fayolle K, et al.
1984 · DOI: 10.1159/000115715 · PMID: 6548969
European Neurology
Larbig W, Gerber WD, Kluck M, Schoenenberger GA
1984 · DOI: 10.1159/000115716 · PMID: 6548970
Neuropsychobiology
Schneider-Helmert D, Schoenenberger GA
1983 · PMID: 6689058
International Journal of Neuroscience
DSIP—a tool for investigating the sleep onset mechanism: a review
Yehuda S, Carasso RL
1988 · DOI: 10.3109/00207458808990695 · PMID: 3286557
Molecules
Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke
Tukhovskaya EA, et al.
2021 · DOI: 10.3390/molecules26175173 · PMID: 34500605
PubChem Database
Research summaries and references are drawn from published, peer-reviewed literature and are provided for educational reference only. They are not product claims or medical advice. This product is sold strictly for laboratory research and is not for human or veterinary use.
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