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Use code RIP30 for 30% off research compounds◉Research use only◉Not for human or veterinary use◉For laboratory research purposes only◉Third-party COA on every batch◉Handle according to applicable laws◉Use code RIP30 for 30% off research compounds◉Research use only◉Not for human or veterinary use◉For laboratory research purposes only◉Third-party COA on every batch◉Handle according to applicable laws◉
Riptide Peptides
Riptide Peptides 5-Amino-1MQ 10mg vial
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Research Peptides

5-Amino-1MQ

≥99% purityLyophilized powderThird-party COA

5-Amino-1MQ is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.

$29.99

Size
1
  • ✓ Same-day dispatch
  • ✓ Discreet packaging
  • ✓ Third-party tested batch
  • ✓ COA available
View Certificate of Analysis →

Certificate of analysis

5-Amino-1MQ is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.

⚠ Research use only. This product is intended solely for in-vitro laboratory research by qualified professionals. Not for human or veterinary use.

Research overview

About 5-Amino-1MQ

Stability Information

Soluble in DMSOAvoid repeated freeze-thawAliquot after reconstitution
Lyophilized (powder)
-20°C · stable 24+ months
Short-term storage
2-8°C · up to 30 days
Reconstituted
2-8°C · use within 7-14 days
Sources & references8 peer-reviewed publications and databases
  1. Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase

    Neelakantan H, Wang HY, Vance V et

    2017 · DOI: 10.1021/acs.jmedchem.7b00389 · PMID: 28548833

  2. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

    Neelakantan H, Vance V, Wetzel MD et al.

    2018 · DOI: 10.1016/j.bcp.2017.11.007 · PMID: 29155147

  3. Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

    Neelakantan H, Brightwell CR, Graber TG et al.

    2019 · DOI: 10.1016/j.bcp.2019.02.008 · PMID: 30753815

  4. Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

    Sampson CM, Dimet AL, Neelakantan H et al.

    2021 · DOI: 10.1038/s41598-021-85051-6 · PMID: 33707534

  5. Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies

    Awosemo O, Neelakantan H, Watowich S et al.

    2021 · DOI: 10.1016/j.jpba.2021.114255 · PMID: 34304009

  6. Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells

    Akar S, Duran T, Azzawri AA et al.

    2021 · DOI: 10.1080/01443615.2020.1854696 · PMID: 33645410

  7. Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice

    Dimet-Wiley A, Wu Q, Wiley JT et al.

    2022 · DOI: 10.1038/s41598-021-03670-5 · PMID: 35013352

  8. Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction

    Babula JJ, Bui D, Stevenson HL et al.

    2024 · DOI: 10.1111/dom.15879 · PMID: 39161060

Research summaries and references are drawn from published, peer-reviewed literature and are provided for educational reference only. They are not product claims or medical advice. This product is sold strictly for laboratory research and is not for human or veterinary use.

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