Stability Information
- Lyophilized (powder)
- -20°C · stable 24+ months
- Short-term storage
- 2-8°C · up to 30 days
- Reconstituted
- 2-8°C · use within 7-14 days

Research Peptides
5-Amino-1MQ is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.
$29.99
Certificate of analysis
5-Amino-1MQ is supplied as a sterile lyophilized powder in a sealed glass vial, manufactured to ≥99% purity. Every batch is verified by independent third-party analysis and ships with a Certificate of Analysis.
⚠ Research use only. This product is intended solely for in-vitro laboratory research by qualified professionals. Not for human or veterinary use.
Research overview
Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
Neelakantan H, Wang HY, Vance V et
2017 · DOI: 10.1021/acs.jmedchem.7b00389 · PMID: 28548833
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
Neelakantan H, Vance V, Wetzel MD et al.
2018 · DOI: 10.1016/j.bcp.2017.11.007 · PMID: 29155147
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
Neelakantan H, Brightwell CR, Graber TG et al.
2019 · DOI: 10.1016/j.bcp.2019.02.008 · PMID: 30753815
Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
Sampson CM, Dimet AL, Neelakantan H et al.
2021 · DOI: 10.1038/s41598-021-85051-6 · PMID: 33707534
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
Awosemo O, Neelakantan H, Watowich S et al.
2021 · DOI: 10.1016/j.jpba.2021.114255 · PMID: 34304009
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
Akar S, Duran T, Azzawri AA et al.
2021 · DOI: 10.1080/01443615.2020.1854696 · PMID: 33645410
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
Dimet-Wiley A, Wu Q, Wiley JT et al.
2022 · DOI: 10.1038/s41598-021-03670-5 · PMID: 35013352
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
Babula JJ, Bui D, Stevenson HL et al.
2024 · DOI: 10.1111/dom.15879 · PMID: 39161060
Research summaries and references are drawn from published, peer-reviewed literature and are provided for educational reference only. They are not product claims or medical advice. This product is sold strictly for laboratory research and is not for human or veterinary use.
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